Bill McDermott, the CEO of software giant SAP in Newtown Square, picked against the school just down the road from his house, the college where his friend, Father Peter Donohue, is president, and the place where he attends Sunday Mass when he’s in town.

Unlike his father and son, who both correctly picked Villanova to win this year’s NCAA Tournament, McDermott chose Kansas, which fell victim to the Wildcats in the Elite Eight, to win it all.

It ended up not mattering, as McDermott flipped his $10,000 bet into a $420,000 windfall for charity by winning Bloomberg LP’s “Brackets for a Cause” pool, writes Joseph DiStefano of the Philadelphia Inquirer.

Like 15 of the 41 other CEOs in the pool, McDermott picked the Jayhawks, betting with his head and not his heart.

The logical choice paid off since none of the contestants selected Villanova to win it.

McDermott donated the pot to the charity of his choice, the Network for Teaching Entrepreneurship, which trains city kids “to develop an entrepreneurial mindset” and pitch business plans.

McDermott had North Carolina, correctly, losing in the final. In all, he picked 46 of the 63 winners, besting No. 2, Starwood Capital boss Barry Sternlicht (who picked 43) and such high-powered competitors as T-Mobile boss John Legere, Salesforce.com founder Marc Benioff, Dallas Mavericks owner Mark Cuban, Goldman Sachs President Gary Cohn, Cisco Systems’ John Chambers, Microsoft cofounder Steve Ballmer, and Bloomberg’s own Michael Bloomberg.

Click here to read more about Bill McDermott’s victory for charity.